Scientists have identified a series of changes in gene expression that appear to predict the onset of Alzheimer’s Disease. A team of researchers from the University of Pennsylvania studied changes in RNA, proteomic profiles, and epigenomics in postmortem brains to identify molecular pathways involved in the neurogenerative disease. Their results, published in the journal Nature Genetics, found that the development of Alzheimer’s involves a reconfiguration of the epigenome. The scientists suspect the discovery could lead to the development of epigenetic strategies for early-stage treatment or prevention of the neurogenerative disease.